Such delayed type hypersensitivity is involved in resistance to certain bacterial and viral infections.
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A delayed type hypersensitivity reaction of cell mediated immunity has been suggested in the pathogenesis of xanthogranulomatous cholecystitis.
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Source ( if applicable ) : ( The first line on the " Type IV hypersensitivity " wiki page states that " delayed type hypersensitivity " is another name for the topic.
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ShK-186, due to its durable pharmacological action, is effective in ameliorating disease in rat models of delayed type hypersensitivity, multiple sclerosis ( experimental autoimmune encephalomyelitis ) and rheumatoid arthritis ( pristane induced arthritis ) when administered once every 2 5 days . ShK-186 has completed non-clinical safety studies.
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Confirming the diagnosis of Ni-ACD specifically involves inducing the skin to demonstrate a rash where the chemicals are applied ( a delayed type hypersensitivity reaction ), evidence that the patient is exposed to nickel, and establishing that the reaction and the exposure explain the current rash / symptoms under question.
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Tuberculin skin testing ( TST ) has been used for years as an aid in diagnosing latent tuberculosis infection ( LTBI ) and includes measurement of the delayed type hypersensitivity response 48 72 hours after intradermal injection of PPD . TST and QFT do not measure the same components of the immunologic response and are not interchangeable.